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DALLAS, Nov. 4, 2003
"Since women reported experiencing early warning signs more
than a month prior to the heart attack, this could allow time
to treat these symptoms and to possibly delay or prevent the
heart attack," said Jean C. McSweeney, Ph.D., R.N., lead author
and a professor in the College of Nursing at the University
of Arkansas for Medical Sciences in Little Rock.
Researchers
recruited 515 women diagnosed with a heart attack and discharged
from five different medical sites in Arkansas, North Carolina
and Ohio within the previous four to six months. The women
were age 66 on average, and 93 percent were Caucasian, 6.2
percent black and 0.4 percent Native American. Data collection
occurred over three years.
To assess symptoms that might suggest
an imminent heart attack, the researchers used the McSweeney
Acute and Prodromal Myocardial Infarction Symptom Survey (MAPMISS),
a telephone research tool developed by McSweeney and her colleagues.
The survey lists 33 early, or prodromal, signs and 37 acute
symptoms that women identified in previous studies. The researchers
defined prodromal signs as being new or changing in intensity
or frequency before the heart attack, being intermittent before
the heart attack, and disappearing or returning to previous
levels after the heart attack. Acute symptoms were defined
as those appearing with the heart attack and not resolving
until women received treatment.
The survey also included questions
about other health problems, risk factors, medications and
demographics. About 95 percent of women reported having new
or different symptoms more than a month before their heart
attacks that resolved after their heart attacks. This led them,
in retrospect, to believe that these symptoms were related
to the subsequent heart attack. The most common early symptoms
were: unusual fatigue -- 70 percent; sleep disturbance -- 48
percent; shortness of breath -- 42 percent; indigestion --
39 percent and anxiety -- 35 percent.
Only 30 percent reported
chest discomfort before their heart attack. They described
the discomfort in terms like aching, tightness and pressure Æ not
pain, McSweeney said.
"Women need to be educated that the appearance
of new symptoms may be associated with heart disease and that
they need to seek medical care to determine the cause of the
symptoms, especially if they have known cardiovascular risks
such as smoking, high blood pressure, high cholesterol, diabetes,
overweight or a family history of heart disease," she said.
Previous research by McSweeney and colleagues found that women
who later identified an array of symptoms occurring before
their heart attacks either ignored the signs or were misdiagnosed
when they sought medical assistance.
McSweeney emphasized the
importance of health care providers being aware of the symptoms
women experience. While these early symptoms may not be specific
in predicting an imminent heart attack, the "appearance of
these symptoms, in conjunction with women's standard cardiovascular
risk factors, may assist providers in determining at-risk women
who should undergo cardiovascular diagnostic tests," she said.
Little has been known about the acute warning signs that women
experience with heart attack, she said. But it is clear that
women's experiences differ from the symptoms they expect.
In
this study, researchers found that 43 percent of women reported
no chest discomfort during their heart attack. For those who
did, the main locations were in the back and high chest.
"Lack
of significant chest pain may be a major reason why women have
more unrecognized heart attacks than men or are mistakenly
diagnosed and discharged from emergency departments," McSweeney
said. "Many clinicians still consider chest pain as the primary
symptom of a heart attack."
Other acute symptoms women reported
were: shortness of breath -- 58 percent; weakness -- 55 percent;
unusual fatigue -- 43 percent; cold sweat -- 39 percent and
dizziness -- 39 percent.
The researchers noted that the study
sample was primarily Caucasian. "We do not know if women's
early warning and/or acute symptoms may vary according to their
race, but we will address this issue with our ongoing study
with minority women," McSweeney explained.
Also, there was
not a control group of women without diagnosed heart disease,
so it is unknown how many of these women might experience similar
preliminary symptoms. Further research is needed to address
these issues.
Co-authors are Marisue
Cody, Ph.D., R.N.; Patricia O'Sullivan, Ed.D.; Karen Elberson,
Ph.D., R.N.; Debra
K. Moser, DNSc, R.N. and Bonnie J. Garvin, Ph.D., R.N. The
National Institute of Nursing Research, part of the National
Institute of Health, funded the study.
ScienceDaily Magazine
Note: This story has been adapted from a news
release issued by American Heart Association.
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